I have killed many, many deer, whitetail and mule deer, with 150gr hornady interlock bullets threw my '06. I have been using them for a long time. They do a lot of damage to the deer, I shoot for tight behind the front shoulder when I can, not much you would want to eat from the ribs. But I want to see damage, I'm more worried about the animal dieing quick, I will sort out the meat issue later. I have only killed one spike bull elk, using the same handload, I found the bullet threw to the other side if the ribs, not quite poking out the hide. The chest cavity was devastated, bull went less than 50yrd. I have a lot of confidence in this load due to seeing alot of on game performance. I must be honest, If I draw a branch antler bull tag, I may bump up to a 165 interlock.
