shouldn't have to move anything except sights.
in a nut shell, here's what i do. others do different, but this is my

1. paper tune. if your shooting drop away rest, you should be shooting darts in the paper. if you don't have a drop away, i suggest getting one. makes life way easier
2. sight in your bow
3. bare shaft test. get your bare shooting same as fletched. do this test to 20 yards
4. readjust sights as required.
5. do all the above and you are good to go.
with your draw length and other variables, your FOC of your arrow might be weird. Let Rav figure that one out for you. i will screw it up if i do. FOC is important for arrow flight stability.