The .300 Win Mag is one of my all time go to cartridges. They like to be pushed hard and are one of the most forgiving cartridges when it comes to seating depth. Most shoot just as well "Jammed" as they do jumped 40 thou.
I will always sacrifice a little bullet weight in a hunting cartridge for a substantial increase in speed. A 165gr Accubond out of a .300 Win Mag @ 3300 plus. Will out do a 180gr bullet any day at typical hunting ranges, I've done it time and time again with both and the 165gr combo is a flat shooting hard hitting big game killing machine.
Give 79grs of RL-22 a try behind a 165gr bullet and work up from there, watch for pressure signs and run it as hot as your rifle will handle it.