Red dot works great with wadcutters for the 38 special. I use 3.4 grains, for a 148 grain Hollow Base Wadcutter, it makes a nice little target/racoon load. If you use a doubled ended wadcutter you can up the load quite a bit, since there is no skirt to blow off the bullet.
As far as .357 I generally use Unique, and the load depends on the bullet.