Took a drive with the wife yesterday evening and encountered a ruffed grouse in the road.  Would have been a chip shot while he was standing in the middle of the road, but I knew the road looped back and all that separated the unseen stretch of road in the background was 2 rows of maple saplings.  I cautiously flanked the wily bird at the low ready until he moved off the road into the hardwood saplings.  I lollipopped his wing joint with the tritium sights and - clean miss.  Sig Sauer P238.  
I try to take as many legal shots on game or varmints as I can with my carry pistols, ever since smoking a coyote at around 9 feet with my first CCW - a Jennings J22 - in 1988.  Over the years - and in states where legal - I've harvested dozens of grouse, squirrels, jackrabbits, cottontails, prairie dogs, feral cats and others with the pistols I carry for personal defense - even when I had a "more suitable" hunting weapon along.  I've taken limits of grouse several times with everything from .22 pocket pistols to a full size M1911 .45.  One year in Wyoming, when the cottontails were cycling at their peak, I took a 10-bunny limit in two hours with 25 rounds of 158gr wadcutters out of a 4" Ruger Security six. Just curious who else does this?  I think it is the best practice in the world for real-world proficiency - and a lot of humbling too.