Low profile for areas with losts of wind. Low Profile for deepest penetration. High Profile for greatest blood trails. Ti-Con or Ultra Con for a happy medium between the other two.
Titanium for best strength, best penetration and just because titanium is cool.

Triple Sec for those who obsess over blade locking security. While still giving you a choice of HPV, LPV or LPS blade styles.
MadMan and Ultra-Con for solid performance without busting a limited budget.
If you want the best for putting animals on the ground quickest...can't tell you which one is better. In all of our testing there has not been enough difference for our team to tell a difference. Ti-Con and Ultra-Con have a slight edge in sharpness due to the thinner blade. But really the entire line are good performers. If one did not hold it's own against the others in effectiveness I would drop it from our line.