[Hey Dansk,
Are you using Dead Center bullets in a 1-48 twist .54?? If so, let's here some stories. I have a traditional hawken and an inline but have not used the Dead Center bullets yet.
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I have an inline TC system1. It's either 1 in 28 or 32...not sure. I bought it right when tc was phasing out their system 1 for the black diamonds with faster twist, 209s, and magnum loads.
Great rifle - sub moa at 50 yds from the bench using 90g pyrodex and 300g PR dead centers when I take my time and shoot well. 2" groups at 100 yds. Zero'd at 175 gives me +4" at 100yds and +2" at 50 and 100 yds. I hold almost 2000ft lbs out to 100yds.
I took a cow elk in 2007 in SW Wa with that setup- my loads were bone crushers- the problem I've found with any inline load I've shot is that they shatter when they hit the spine, shoulder, etc, and ruin alot of meat. It takes the animal down, but makes a mess. I always find lead in my ground if it's not a soft tissue pass through.
The cool think about PR is that they make a bullet/sabot combo for almost any set-up. I'm looking at a chart I have from them- says the optimum combo for 1in48 is a 300g .45 cal bullet.