My vote is for savage. I have a trophy hunter in 30-06. I also have an axis in .223, and have had a bunch on their rimfires over the years. All extremely accurate.
I am able to put rounds in one hole from 100yards with factory ammo. You get a lot for your money with the savage. I am huge Ruger fan as well, however I feel the savages are more accurate out of the box and the accutrigger is amazing. The 110 action they use on the trophy hunter is a time proven design and mine shoots lights out. This gun compares to Remington 700 type action whereas the American compares to the Axis type action. To me it feels a little more refined and of higher quality than the American.