When it's pouring rain, and I'm in the woods, I like to take out the AR15 in a 30/.223 wildcat. Ballistics wise it's a 30/30 with a 150gr round nose at 2250fps, with a Leupold VXIII 1.5x5.
Better weather and more open terrain it's a 1970's Ruger M77 Tanger in .270win. with a Leupold 3x9 with 140 gr Barnes.
If I had to choose just one for all season, it's the old Ruger. It's a tack driver with flat trajectory and enough power to cleanly put down game much further than I'll ever shoot, without getting kicked hard.