I shot this buck at 269 with my 45 caliber peep sighted muzzy. The only reason I consider the shot was, because the buck was standing broadside on the skyline of a ridge so he was very easy to see clearly through the peep., I had a solid prone rest, there was no way I was going to get closer because he had spotted me already,and of course I practiced with the gun a lot that season. I know guys that muzzy hunt and never practice and wound or miss at 75. It all comes down to practice and knowing your limits.