You can hunt the same spot within the hour I'd say. The above comments are right that you can expect multiple toms/jakes to come in at once this time of year. You can go for the ol' 1,2,3, shoot or you can prime your kids that Joe is shooting first but we dont move and if Bob can shoot he then will shoot. More often then not the birds will jump at the sound of the gun firing, start looking around with what the heck confusion, then boogy or turn and start picking on their dead pal. Bob can shoot during the what the heck moment or during the turn on their buddy moment.
Often though turkeys from the same or seperate flock will use the same travel routes. I busted up 20 birds to kill one, took it back to my truck, came back and sat down for a second flock to walk in 45 minutes later and kill another bird.
The biggest thing to this IMO is that you dont start hoot'n and holler'n after you kill the first bird. Wait for all eyes to move off before you go to retrieve it, then sit back down and start hunting again. Only think I wouldnt do is shoot at a bird in a flock, then chase them to try to shoot them again. Let them or others to come back later or the next day.
Good luck!