I shoot Federal Premium High Energy 180 gr Noslers out of my 30-06. It basically turns my 30-06 into a .300 Win Mag. as both have the same ballistics. The good and bad are I can always shoot the cheaper and readily avail 30-06 ammo, the bad is the $45-$50 a box high energy rounds. IMO you can't go wrong with a 30-06.
Also IMO 165gr to 180Gr is a perfect all round weight for most game