Rule Three Reminder:
"Always confirm your target, and what's beyond it."
I had a chance at a 4 point bruiser of a mule deer last year. I didn't take the shot because there was an area 500 yards away behind the deer that may have had some people. It was the toughest self-restraint call I've ever made, but I didn't take the shot.
There is no way to call back a bullet!