I tinkered with many bullets and charges when I got into muzzy about 10-ish years ago. As stated, those SSTs group slightly better than anything else. But what I've landed on for hunting is the Barnes TMZs in 250 grain (with 100 -110 grains of loose powder).
For both deer and elk, this load has been devastating. The copper petals peel back perfectly to form a wider surface area and each petal edge forms a sharp cutting surface. How do I know? They stay 100% intact most of the time and don't always pass completely through. I've recovered a few in the off side shoulder, neck, against the hide, etc.
Accuracy is only reason I circled back to the Hornady SST. They somehow just seem more consistent/less 'touchy'?