no problem. A 40 gr v-max out of the hornet kills them dead on the spot. Unless you blow there leg off. The can still run preatty fast on 3 legs. 
3 ?? I have had them out run me with two legs. Ask duckfvr and 509er. Duck had to kill it with a rock. That sucker had no front legs. He just plowed snow for 400 yards and fast!!!