Helped a guy out who hurt his back between hunting trips and couldn't go get his trailer from the mountains. Not a big, heavy trailer, I would have used my F150 but since he offered for me to just take his couple year old F350 with the 6.7 I said sure. Engine and transmission was great, but oh my that's a stiff ride! Without a heavy load, uncomfortably harsh, especially on rutted up, washboard sections. Got back in my F150, amazing difference in comfort!
Do you want a dedicated towing truck that gives up a lot for daily stuff? Or want an every day truck that gives up some in towing? Either way you're going to give something up.
I wouldn't buy an F350 after driving that for 7 hours yesterday. Curious how an F250 would compare