Yeah, my comment about a neck shot being a poor choice is only in regards to elk. Deer are totally different. And it's also somewhat different when you're shooting a modern firearm with a velocity of 3000 feet per second, versus a muzzleloader which is probably around 1500 feet per second.
I shot my .50 using 290 grs Barns TMZ with 120 grains of powder and got about 2300fps for vol.