I always shoot Nosler Partitions or better. To me, they are the base line. Sure, plenty of game has been dropped with CoreLokt ammo, and plenty more will be. Put one of those into the boiler room and it's all over. But.... as we all know, sometimes things don't happen exactly as we hope. For those reasons, I want an advantage. I wait 350 days between hunts, I spend a pile on gear, tags, time off, guns, etc. Is it really that smart to then skimp on ammo? Pay 1 dollar more per shot and shoot the best, most proven ammo for the game you are after. If you are on a dime a dozen deer hunt, maybe the Corelokt stuff is ok. But if you are in AZ, chasing strip bucks after waiting 30 years for a tag... I don't think so. Same goes for larger animals, and Ben's post is a perfect example of why.
The '06 will smoke any moose, but unless you can get a tag easily each year... why would you want to chase one under gunned? You're either on a OIL hunt, or paying a guide a truck load of money. I hereby give you permission to upgrade your arsenal. 338 Win Mag with 210 Noslers will do nicely!