I had a 338 Win. when I lived in Alaska. I am not a great shot just as Huntwa, but I did get a few critters with the 338. My best shot was a caribou that a buddy had wounded and was running away. I caught it at the top of the tail...the bullet followed the spine through the diaphram, lungs, heart and out the chest. Exit wound was big enough to pass a football though. I did that at 400 yards...never do it again either, just plain ass good luck.
The next caribou I shot at about 50 yards. go figure?

He came over to see what we were doing to his buddy.