I shoot a 58grain Hornady v-max out of my 243. It is going about 3700fps at the muzzle. I haven't shot it past 400 yards but at that distance there is about 16 inches of drop. It is a very destructive bullet though so if pelt damage is an issue than I don't recommend it. The v-max also comes in 65,75, and 87 grains so the heavier might not be as destructive. Super accurate as well.