Like was stated 0 point units for the most part are going to be a tough go. Definitely doable with some work, but typically either lots of pressure, limited public land or not a lot of deer, which is why they're zero points. It's still CO though and big bucks are killed in 0 point units every year. There is no random draw so having even 1 or 2 points opens up quite a few more options for some decent hunts.
Another option would be landowner tags, but they are getting pretty spendy these days. These don't require a guide if you buy a unit-wide one