If you have been hunting, you probably already have (or should have ) reconciled the fact that you risk wounding target animals with every shot. Nothing about which weapon your using changes that, just different parameters.
Become very familiar with the area your hunting. In terms of success I would prefer to have a few elk in an area I know inside and out, than more elk in a strange area. The way wind moves at different times of day and weather fronts, where the elk go when pushed, feed areas in early vs late season. Knowing about a small spine ridge, or small creek bottom can mean the difference between getting in elks wheel house, or being a hundred yards away from them with no way to get closer.