Free: Contests & Raffles.
I say it depends how far out you plan on shooting, If you look at the Remington balistic calculator and compare he long range dropp of a 125 grain bullet and a 180 grain at 300 yrds its 1.4 in, 400yrds there is only 2.5" diff and @500 a 4.5in diff So out to 300 yards there is really not any significant difference. I have my 06 sited in with 165 grain so its a split the difference if i go up or down... But i usually shoot military ball at coyotes so i don't really care.
Another Noob question: If you change bullets, say 165gr to 180gr, do you have to redial your scope?