The bull I killed with a 30-06 I shot with a 150gr Hornaday Interlock. After the shot, it took a few steps and fell over. A few death kicks on the ground, lights out. That said, a 165gr Accubond would be a great choice. I dont think I would consider a 180 unless after moose, and then, I'd still probably use the 165 Accubond.