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If she has small hands the Walther P22 is great. New they are about $350, and come in pink if that is what she likes. But otherwise the Rugers are great.
Ruger hunter is a keeper for me. Good lookin, comfortable, and accurite as hell
Would have to agree with Jethro. If she does not have extensive firearms training go with a revolver.( This goes for men as well as women) I have been a firearms Instructor for over 15 years and always suggest single shot rifle/ shotgun and/ or revolver for the first few years. I got my wife a .22 mag revolver. She likes it. When she demonstrates that she can safely handle a firearm will get her a semi-auto.Cannot over emphasize firearms safety! Look at S&W, Taurus, RugerShe will have funGood luck