Free: Contests & Raffles.
I have both of these calibers, and I like both of them very much. With that being said, my preferance would be the 22/250. The reason being, less wind drift at longer range, as well as a heavier bullet. My 204 does wonders, but only when the wind isnt blowing. I also second the vote for the .243, or better yet the 260 rem. Sage