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I have a 243 win. savage model 10 and I use imr4831, hornady brass and 95 gr. sst bullets and 43gr. powder and I shoot a dime all day long at 100 yards. A silver dollar at 300 yards. This is with using a sled. Using a bipot I shoot nickle groups at a hundred yards. It seems to work for me and I tried a lot of different powders and this setup works for me for preditor and deer.
Varget is like butter....Makes just about everything a little better.H414 is another good choice.Seriously Varget and the 51mm case were just about made for each other.