I have killed deer with my 243 and 95 gr nosler BT's, 95gr sst's, 95gr vld's and 105 vld's. From 5 yards to 200 yards Many drt never had one go more than 60 yards. The vld's have been my favorite. Have taken few black bear as well both about 180 yards. First went 40 yards, second one rag dolled down the mountian about 100 yards. What ever bullet shoots best in your rifle will be a great choice