:)243 knocks coyotes down HARD, much more than my 22-250 and is just as flat. I shot a few deer with it one buck was laying down looking at me about 200 yards, his body was pointed at me, I shot him in the front of the neck just under his muzzle, the 80 grain bullet flipped him clear over on his back, legs sticking up in the air and not even a tiny kick of his feet.
I am real happy with it, very effective on both.
Carl